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We have observed that Microsoft defender causes high CPU usage in SAP applications. Also when it scans the exe files, the users are reporting performance issues. The issue is already identified by SAP . The solution is to exclude all SAP related folders from scanning by microsoft defender.

Which files and directories should be a part of Antivirus exclusion list on Windows

Microsoft Defender Endpoint (MDE) for SAP Applications on Windows Server
How To: Run Process Monitor With Reduced Altitude | SAP Blogs

For SAP BO the following note will help
1497394 – Which files and directories should be excluded from an antivirus scan for SAP BusinessObjects Business Intelligence Platform products in Windows?

There is a troublshooting tree related to it
Check if there is an Antivirus blocking the email request. – SAP BusinessObjects Report schedules to Email Destination fails. – Guided Answers